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PE Anti-Mouse/Human CD11b Antibody

Product Specifications

Background

CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

CAS Number

9007-83-4

Synonyms

Integrin alpha-M, Itgam, CD11 antigen-like family member B, CR-3 alpha chain, Leukocyte adhesion receptor MO1, CD11b

Gene ID

16409,3684

Swiss Prot

P05555, P11215

Host

Rat

Reactivity

Human, Mouse

Isotype

IgG2b κ

Conjugation

PE

Applications

FCM

Concentration

0.2 mg/mL

Buffer

PBS with 0.05% Proclin300, 1% BSA

Storage Conditions

Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Available Sizes

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