GKK1032B
GKK1032B is an alkaloid compound that can be found in endophytic fungus Penicillium sp. GKK1032B can induce the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation[1].
Product Specifications
CAS Number
358375-11-8
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gkk1032b.html
Solubility
10 mM in DMSO
Smiles
C[C@]1(C[C@@H]2C)[C@@](C(C)=C3)([H])[C@]([C@](C([C@@](C(N4)=O)([H])[C@](C4=O)([H])C5)=O)([H])[C@@]3(C)C=C)([H])[C@@](OC6=CC=C5C=C6)([H])[C@]1([H])[C@H](C2)C
Molecular Formula
C32H39NO4
Molecular Weight
501.66
References & Citations
[1]Qi X, et, al. GKK1032C, a new alkaloid compound from the endophytic fungus Penicillium sp. CPCC 400817 with activity against methicillin-resistant S. aureus. J Antibiot (Tokyo) . 2019 Apr;72 (4) :237-240.|[2]Liu N, et, al. GKK1032B from endophytic Penicillium citrinum induces the apoptosis of human osteosarcoma MG63 cells through caspase pathway activation. Chin J Nat Med. 2022 Jan;20 (1) :67-73.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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