Recombinant Human ROBO1 Protein (ECD, His Tag)

<strong>Recombinant Human ROBO1 Protein (ECD, His Tag)</strong>_x000D_ <strong>Catalog number:</strong> B2019140_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 97.08 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> CPHD8 Protein, Human; DUTT1 Protein, Human; FLJ21882 Protein, Human; NORS Protein, Human; NYS8 Protein, Human; SAX3 Protein, Human_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Chen CY, Tsai CH, Chen CY, Wu YH, Chen CP. Human placental multipotent mesenchymal stromal cells modulate placenta angiogenesis through Slit2-Robo signaling Cell Adh Migr. 2016 Mar 3;10(1-2):66-76._x000D_ 2: Zhou WJ, Geng ZH, Chi S, Zhang W, Niu XF, Lan SJ, Ma L, Yang X, Wang LJ, Ding YQ, Geng JG. Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis Cell Res. 2011 Apr;21(4):609-26._x000D_ 3: Kim BJ, Lee YS, Lee SY, Baek WY, Choi YJ, Moon SA, Lee SH, Kim JE, Chang EJ, Kim EY, Yoon J, Kim SW, Ryu SH, Lee SK, Lorenzo JA, Ahn SH, Kim H, Lee KU, Kim GS, Koh JM. Osteoclast-secreted SLIT3 coordinates bone resorption and formation J Clin Invest. 2018 Apr 2;128(4):1429-1441._x000D_ 4: Mano Y, Aishima S, Fukuhara T, Tanaka Y, Kubo Y, Motomura T, Toshima T, Iguchi T, Shirabe K, Maehara Y, Oda Y. Decreased roundabout 1 expression promotes development of intrahepatic cholangiocarcinoma Hum Pathol. 2013 Nov;44(11):2419-26._x000D_ 5: Glawe JD, Mijalis EM, Davis WC, Barlow SC, Gungor N, McVie R, Kevil CG. SDF-1-CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1-SLIT2 interactions in mice Diabetologia. 2013 Oct;56(10):2222-30._x000D_ 6: Zhang QQ, Zhou DL, Lei Y, Zheng L, Chen SX, Gou HJ, Gu QL, He XD, Lan T, Qi CL, Li JC, Ding YQ, Qiao L, Wang LJ. Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway Oncotarget. 2015 Feb 20;6(5):3123-35._x000D_ 7: Li Y, Fu S, Chen H, Feng Q, Gao Y, Xue H, Ge Z, Fang J, Xiao S. Inhibition of endothelial Slit2/Robo1 signaling by thalidomide restrains angiogenesis by blocking the PI3K/Akt pathway Dig Dis Sci. 2014 Dec;59(12):2958-66._x000D_ 8: Yumura K, Akiba H, Nagatoishi S, Kusano-Arai O, Iwanari H, Hamakubo T, Tsumoto K. Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen J Biochem. 2017 Sep 1;162(3):203-210._x000D_ 9: Mertsch S, Schmitz N, Jeibmann A, Geng JG, Paulus W, Senner V. Slit2 involvement in glioma cell migration is mediated by Robo1 receptor J Neurooncol. 2008 Mar;87(1):1-7._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20298689">10: Han X, Zhang MC. Potential anti-angiogenic role of Slit2 in corneal neovascularization Exp Eye Res. 2010 Jun;90(6):742-9. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant Human ROBO1 Protein (ECD, His Tag) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>