Isometronidazole
Isometronidazole is a hypoxic cell sensitizer. Isometronidazole (750 mg/kg) shows an efficacy as a hypoxic cell sensitizer in severely hypoxic FaDu tumors but not in less hypoxic GL tumors.
Product Specifications
CAS Number
[705-19-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isometronidazole.html
Purity
99.20
Solubility
10 mM in DMSO
Smiles
CC1=NC(=CN1CCO)[N+](=O)[O-]
Molecular Formula
C6H9N3O3
Molecular Weight
171.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Schreiber A, et al. Effect of the hypoxic cell sensitizer isometronidazole on local control of two human squamous cell carcinomas after fractionated irradiation. Strahlenther Onkol. 2004;180 (6) :375-382.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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