Solanesol
Solanesol is an orally active aliphatic terpene alcohol. Solanesol is mainly found in tobacco and other Solanaceae plants. Solanesol induces HO-1 and Hsp70 expression, activates p38 and Akt signaling pathways, and inhibits Apoptosis (reduces caspase-3 and PARP cleavage) . Solanesol has antioxidant, anti-inflammatory, and neuroprotective activities. Solanesol can be used in the research of Huntington's disease, alcoholic liver disease, chronic inflammatory pain, anxiety, Alzheimer's disease, and bipolar disorder[1][2][3][4][5][6][7][8].
Product Specifications
CAS Number
13190-97-1
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Akt; Apoptosis; Caspase; Endogenous Metabolite; Heme Oxygenase (HO) ; HSP; p38 MAPK; PARP
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/solanesol.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C/C(C)=C\CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CO
Molecular Formula
C45H74O
Molecular Weight
631.07
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3; HO-1; HSP70
Available Sizes
Frequently Asked Questions
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