NO-IN-1
Product Specifications
UNSPSC Description
NO-IN-1 (Compound 7a) inhibits the production of NO (IC50 = 3.13 μΜ). NO-IN-1 has anti-inflammatory effects. NO-IN-1 downregulates the expression of COX-2 and iNOS by inhibiting the NF-κB signaling pathway[1].
Target Antigen
COX; NF-κB; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation;NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/no-in-1.html
Smiles
O=C(OCC1=CN(CCN2C(C(C3=C2C=CC=C3)=O)=O)N=N1)C/C(C=O)=C\C[C@H]4C(CC[C@@]5([H])C(C)(C)CCC[C@]45C)=C
Molecular Weight
572.69
References & Citations
[1]Mohan S, et al. Ligand-Based Pharmacophoric Design and Anti-inflammatory Evaluation of Triazole Linked Semisynthetic Labdane Conjugates[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163888/NO-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163888/
Clinical Information
No Development Reported
Curated Selection
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