Elinogrel (potassium)

Elinogrel (PRT060128) potassium is a reversible, competitive and orally active P2Y12 antagonist. Elinogrel potassium inhibits thrombosis[1][2].

Product Specifications

CAS Number

[936501-01-8]

Product Name Alternative

PRT060128 (potassium)

UNSPSC

12352005

Target

P2Y Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/elinogrel-potassium.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC=C(Cl)S1)(NC(NC2=CC=C(N3C(NC4=C(C=C(F)C(NC)=C4)C3=O)=O)C=C2)=O)=O.[K]

Molecular Formula

C20H15ClFKN5O5S2

Molecular Weight

563.04

References & Citations

[1]Ueno M, et al. Elinogrel: pharmacological principles, preclinical and early phase clinical testing. Future Cardiol. 2010 Jul;6 (4) :445-53.|[2]Haberstock-Debic H, et al. A clopidogrel-insensitive inducible pool of P2Y12 receptors contributes to thrombus formation: inhibition by elinogrel, a direct-acting, reversible P2Y12 antagonist. J Pharmacol Exp Ther. 2011 Oct;339 (1) :54-61.