D-Lin-MC3-DMA (Excipient)

Product Specifications

CAS Number

[1224606-06-7]

UNSPSC Description

D-Lin-MC3-DMA Excipient, an ionizable cationic lipid, is a potent siRNA delivery vehicle.

Target Antigen

Liposome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/d-lin-mc3-dma-excipient.html

Smiles

O=C(OC(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC)CCCN(C)C

Molecular Weight

642.09

References & Citations

[1]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19(7):2175-2182. |[2]Kulkarni JA, et al. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine. 2017 May;13(4):1377-1387.