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EGFR-IN-122

EGFR-IN-122 (compound Yfq07) is a potent EGFR inhibitor. EGFR-IN-122 suppresses the proliferation of PC-9GR and HCC827GR cells[1].

Product Specifications

CAS Number

1807453-44-6

UNSPSC

12352211

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-122.html

Smiles

COC1=CC(NC2=CC(NC3=CC(OC)=CC=C3)=NC=N2)=C(OC)C=C1

Molecular Formula

C19H20N4O3

Molecular Weight

352.39

References & Citations

[1]Zhang Y, et al. Inhibition of DDR1 promotes ferroptosis and overcomes gefitinib resistance in non-small cell lung cancer. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870 (7) :167447.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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