Glycine-13C2,15N,d2
Product Specifications
UNSPSC Description
Glycine-13C2,15N,d2 is the deuterium, 13C and 15N labeled Glycine[1]. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[2].
Target Antigen
Endogenous Metabolite; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
[15NH2][13C]([2H])([2H])[13C](O)=O
Molecular Weight
80.06
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1984075-49-1
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