Butane-1,4-diyldiphosphonic acid

Butane-1,4-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[4671-77-6]

UNSPSC

12352211

Hazard Statement

H290, H314

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/butane-1-4-diyldiphosphonic-acid.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

OP(CCCCP(O)(O)=O)(O)=O

Molecular Formula

C4H12O6P2

Molecular Weight

218.08

Precautions

H290, H314

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Available Sizes

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