Pyr-Pro-Arg-pNA
Pyr-Pro-Arg-pNA (S2366) is a chromogenic peptide substrate for Factor XI and Activated protein C (APC) . Pyr-Pro-Arg-pNA can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA can be used for measurement of APC amidolytic activity[1][2].
Product Specifications
CAS Number
[72194-57-1]
Product Name Alternative
S-2366
UNSPSC
12352005
Target
APC; Biochemical Assay Reagents; Factor XI
Type
Peptides
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pyr-pro-arg-pna.html
Smiles
O=C([C@@H]1CCC(N1)=O)N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(NC3=CC=C(C=C3)[N+]([O-])=O)=O)=O
Molecular Formula
C22H30N8O6
Molecular Weight
502.52
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Peptides
Clinical Information
No Development Reported
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