N3-L-Val-OH (CHA)
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir) [1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Product Specifications
CAS Number
[1217462-63-9]
Product Name Alternative
L-azidovaline (CHA)
UNSPSC
12352211
Hazard Statement
H315-H319-H335
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n3-l-val-oh-cha.html
Purity
99.15
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
NC1CCCCC1.[N-]=[N+]=N[C@H](C(O)=O)C(C)C
Molecular Formula
C11H22N4O2
Molecular Weight
242.32
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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