N3-L-Val-OH (CHA)
Product Specifications
UNSPSC Description
N3-L-Val-OH (CHA) is a click chemistry containing an azide group, a valine derivative. N3-L-Val-OH (CHA) can also be used as a synthetic intermediate for Valaciclovir (Valacyclovir)[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
Target Antigen
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/n3-l-val-oh-cha.html
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
NC1CCCCC1.[N-]=[N+]=N[C@H](C(O)=O)C(C)C
Molecular Weight
242.32
References & Citations
[1]Hassan M Faidallah, et al. Synthesis, antibacterial properties and 2D-QSAR studies of quinolone-triazole conjugates. Eur J Med Chem. 2018 Jan 1;143:1524-1534.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151661/N3-L-Val-OH-CHA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151661/N3-L-Val-OH-CHA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1217462-63-9
Available Sizes
Curated Selection
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