Atecegatran
Atecegatran (AR-H067637) is an orally active competitive thrombin inhibitor with a Ki of 2-4 nM. AR-H067637 inhibits platelet activation and aggregation by blocking thrombin binding to fibrin and thrombomodulin. Atecegatran demonstrates significant anticoagulant effects in various plasma coagulation assays, with an IC50 ranging from 93 to 220 nM. Atecegatran can be used in research related to thromboembolic disorders[1].
Product Specifications
CAS Number
433937-74-7
Product Name Alternative
AR-H067637
UNSPSC
12352005
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/atecegatran.html
Smiles
O=C([C@H](O)C1=CC(OC(F)F)=CC(Cl)=C1)N(CC2)[C@@H]2C(NCC3=CC=C(C=C3)C(N)=N)=O
Molecular Formula
C21H21ClF2N4O4
Molecular Weight
466.87
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Arabidopsis thaliana Putative B3 domain-containing protein At2g31460 (At2g31460)
Recombinant Arabidopsis thaliana Putative B3 domain-containing protein At2g31460 (At2g31460)
Recombinant Arabidopsis thaliana Putative B3 domain-containing protein At2g31460 (At2g31460)