BiBET
BiBET is a chemical probe of BET/BRD4 and is able to bind to two bromodomains simultaneously in a bivalent and cis-binding mode[1].
Product Specifications
CAS Number
[2059110-46-0]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bibet.html
Smiles
CN(CCOC1=CC=C(C2CCN(C3=NN4C(C=C3)=NN=C4OC)CC2)C=C1)C5=NN6C(C=C5)=NN=C6OC
Molecular Formula
C26H30N10O3
Molecular Weight
530.58
References & Citations
[1]Waring M J, et al. Potent and selective bivalent inhibitors of BET bromodomains[J]. Nature chemical biology, 2016, 12 (12) : 1097-1104.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-123626/BiBET-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-123626/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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