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BiBET

BiBET is a chemical probe of BET/BRD4 and is able to bind to two bromodomains simultaneously in a bivalent and cis-binding mode[1].

Product Specifications

CAS Number

[2059110-46-0]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bibet.html

Smiles

CN(CCOC1=CC=C(C2CCN(C3=NN4C(C=C3)=NN=C4OC)CC2)C=C1)C5=NN6C(C=C5)=NN=C6OC

Molecular Formula

C26H30N10O3

Molecular Weight

530.58

References & Citations

[1]Waring M J, et al. Potent and selective bivalent inhibitors of BET bromodomains[J]. Nature chemical biology, 2016, 12 (12) : 1097-1104.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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