Human CD45RO Protein, His Tag (MALS verified)
CD45RO contains exon 3, 7 and 8 and lacks the RA, RB and RC exons of the CD45 gene. CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.
Product Specifications
Background
Specifications
Accession Number
P08575-4
Expression Region
Gln 26 - Lys 416
Host
HEK293
Target
CD45RO
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
46.4 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Host or Source
HEK293
Species
Human
Protein ID
P08575-4
Preservative
Trehalose
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