Dafsolimab
Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3) . Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) [1].
Product Specifications
CAS Number
2367001-71-4
Product Name Alternative
SPV-T3a
UNSPSC
12352203
Target
CD3
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dafsolimab.html
Purity
97.31
Solubility
10 mM in DMSO
Smiles
[Dafsolimab]
Molecular Weight
(146.472 kDa)
References & Citations
[1]van Oosterhout YV, et al. A combination of anti-CD3 and anti-CD7 ricin A-immunotoxins for the in vivo treatment of acute graft versus host disease. Blood. 2000 Jun 15;95 (12) :3693-701.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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