Mcl-1 (phospho-Ser159/Thr163) rabbit pAb
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010],
Product Specifications
Background
Product Name Alternative
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
UniProt
Q07820
Swiss Prot
Q07820
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human Mcl-1 (Ser159 and Thr163)
Target
Mcl-1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
About 40kd in human,39kd in mouse and rat
Storage Conditions
-20°C/1 year
Observed Molecular Weight
About 40kd in human,39kd in mouse and rat
Fragment
IgG
Subcellular Location
Membrane ; Single-pass membrane protein . Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Cytoplasmic, associated with mitochondria.
Other Product Names
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Gene ID (Human)
4170
Available Sizes
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