Tat-beclin 1 (TFA)

Tat-beclin 1 TFA, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2) . Tat-beclin 1 TFA decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV) [1].

Product Specifications

UNSPSC

12352209

Target

Autophagy; CHIKV; HIV

Type

Peptides

Related Pathways

Anti-infection; Autophagy

Applications

Cancer-programmed cell death

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tat-beclin-1-tfa.html

Solubility

H2O

Smiles

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