Rabbit anti Human Protein Phosphatase 2 A/B gamma

Product Specifications

Background

Protein phosphatase 2A (PP2A) is a hetertrimeric enzyme consisting of a catalytic subunits (C), a structural subunit (A) and a variable regulatory subunit (B). The B subunit family is made up of the , and isoforms. The PP2A/B isoform appears to only be detectable in the brain where it has been speculated that it cytoskeletal substrates. The RNA which produces the PP2A/B is developmentally regulated and increases sharply after birth. It has also been suggested that it may be important in the establishment and maintenance of neuronal connections.

CAS Number

9007-83-4

Synonyms

Protein Phosphatase 2 A/Bγ2

UniProt

Q13362 (Human), P97888 (Rat), Q8BG02 (Mouse)

Host

Rabbit

Species Reactivity

Human,Mouse,Rat,Bovine

Isotype

IgG

Conjugation

Unconjugated

Type

Polyclonal Antibody

Applications

Field of Research

Signal Transduction

Purification Method

Ammonium Sulfate Precipitation

Assay Principle

Detects PP2A/B isoforms by Western blot analysis. Detects a 56 kDa band in whole rat brain homogenates. Optimal concentration should be evaluated by serial dilutions.

Stability

See expiration date on vial

Concentration

See vial for Concentration

Form

Provided as solution in phosphate buffered saline with 0,08% sodium azide

Precautions

This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving Humans or animals.

References & Citations

1. Strack, S., et al. Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits. J. Comp. Neurol. 1998, 392, 515-527