Antiangiogenic agent 7
Antiangiogenic agent 7 (Compound 1) can induce cell apoptosis, increase Reactive Oxygen Species, and inhibit the intracellular enzyme thioredoxin reductase. Antiangiogenic agent 7 has anti-cancer activity, with an IC50 of 0.08-3.5 μM against cervical cancer cells HeLa, prostate cancer cells PC-3, and non-small cell lung cancer A549. Antiangiogenic agent 7 inhibits tumor growth in mouse xenograft models[1].
Product Specifications
CAS Number
2527888-07-7
UNSPSC
12352005
Target
Apoptosis; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antiangiogenic-agent-7.html
Smiles
S=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=C([Au][P@@]4(C5)CN(C6)C[N@]5C[N@@]6C4)C=CC=C3
Molecular Formula
C24H26AuN3P2S
Molecular Weight
647.46
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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