Human Alpha Thrombin

<strong>Human Alpha Thrombin</strong>_x000D_ <strong>Catalog number:</strong> B2013829_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1000 units_x000D_ <strong>Molecular Weight or Concentration:</strong> 37 kDa_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Human Alpha Thrombin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Bishop PD, Lewis KB, Schultz J, Walker KM. Comparison of recombinant human thrombin and plasma-derived human alpha-thrombin Semin Thromb Hemost. 2006 Apr;32 Suppl 1:86-97._x000D_ 2: Kolodzeiskaya MV, Sokolovskaya LI, Volkov GL. Role of A-chain in functioning of the active site of human alpha_thrombin Biochemistry (Mosc). 2008 Mar;73(3):237-44._x000D_ 3: Meta A, Hirashima M, Imamura T, Kawamura R, Yano K, Uehara K, Nakashima T. High-yield preparation of recombinant human _thrombin for therapeutic use J Biosci Bioeng. 2015 Oct;120(4):432-7._x000D_ 4: Schmaier AH, Meloni FJ, Nawarawong W, Jiang YP. PPACK-thrombin is a noncompetitive inhibitor of alpha_thrombin binding to human platelets Thromb Res. 1992 Sep 1;67(5):479-89._x000D_ 5: Bezeaud A, Denninger MH, Guillin MC. Interaction of human alpha_thrombin and gamma-thrombin with antithrombin III, protein C and thrombomodulin Eur J Biochem. 1985 Dec 16;153(3):491-6._x000D_ 6: Deng N, Jiang B, Chen Y, Liang Z, Zhang L, Liang Y, Yang K, Zhang Y. Aptamer-conjugated gold functionalized graphene oxide nanocomposites for human_thrombin specific recognition J Chromatogr A. 2016 Jan 4;1427:16-21._x000D_ 7: Troisi R, Balasco N, Vitagliano L, Sica F. Molecular dynamics simulations of human_thrombin in different structural contexts: evidence for an aptamer-guided cooperation between the two exosites J Biomol Struct Dyn. 2021 Apr;39(6):2199-2209._x000D_ 8: Witting JI, Miller TM, Fenton JW 2nd. Human alpha_ and gamma-thrombin specificity with tripeptide p-nitroanalide substrates under physiologically relevant conditions Thromb Res. 1987 May 15;46(4):567-74._x000D_ 9: Fenton JW 2nd, Olson TA, Zabinski MP, Wilner GD. Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition Biochemistry. 1988 Sep 6;27(18):7106-12._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/3745265">10: Harlan JM, Thompson PJ, Ross RR, Bowen-Pope DF. Alpha-thrombin induces release of platelet-derived growth factor-like molecule(s) by cultured human endothelial cells J Cell Biol. 1986 Sep;103(3):1129-33. </a>_x000D_ _x000D_ <strong>Products Related to Human Alpha Thrombin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>