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Atg14 (phospho-Ser29) rabbit pAb

Product Specifications

Synonyms

Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)

Gene ID

22863

UniProt

Q6ZNE5

Cellular Locus

Cytoplasm. Endoplasmic reticulum membrane ; Peripheral membrane protein. Preautophagosomal structure membrane ; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein. Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse

Reactivity

Human; Mouse

Immunogen

Synthesized phosho peptide around human Atg14 (Ser29)

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1:1000-2000

Molecular Weight

55kD

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES18207-1.pdf

Observed Molecular Weight

55 kD

Subcellular Location

Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071) . Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071) . Accumulates on highly curved PtdIns (3) P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .

Other Product Names

Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)

Gene ID (Human)

22863

SwissProt (Human)

Q6ZNE5

Available Sizes

Curated Selection

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