Atg14 (phospho-Ser29) rabbit pAb
Product Specifications
Synonyms
Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)
Gene ID
22863
UniProt
Q6ZNE5
Cellular Locus
Cytoplasm. Endoplasmic reticulum membrane ; Peripheral membrane protein. Preautophagosomal structure membrane ; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein. Cytosolic under nutrient-rich conditions (PubMed:19050071). Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071). Accumulates on highly curved PtdIns(3)P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity)..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized phosho peptide around human Atg14 (Ser29)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Molecular Weight
55kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES18207-1.pdf
Observed Molecular Weight
55 kD
Subcellular Location
Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein . Preautophagosomal structure membrane ; Peripheral membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Peripheral membrane protein . Cytosolic under nutrient-rich conditions (PubMed:19050071) . Following autophagy stimuli, such as starvation or rapamycin induction, predominantly detected in cytoplasmic foci, identified as isolation membranes and autophagosomes (PubMed:19050071) . Accumulates on highly curved PtdIns (3) P enriched autophagic membrane via its BATS domain to sense and maintain membrane curvature (By similarity) . Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity) . .
Other Product Names
Beclin 1-associated autophagy-related key regulator (Barkor) (Autophagy-related protein 14-like protein) (Atg14L)
Gene ID (Human)
22863
SwissProt (Human)
Q6ZNE5
Available Sizes
Curated Selection
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