Bicuculline (Standard)
Bicuculline (Standard) is the analytical standard of Bicuculline. This product is intended for research and analytical applications. Bicuculline ((+) -Bicuculline) is A competing neurotransmitter GABAA receptor antagonist (IC50=2 μM) . Bicuculline also blocks Ca2+ activating potassium (SK) channels and subsequently blocks slow post-hyperpolarization (slow AHP) . Bicuculline has anticonvulsant activity. Bicuculline can be used to induce seizures in mice[1][2][3][4].
Product Specifications
CAS Number
485-49-4
Product Name Alternative
(+) -Bicuculline (Standard)
UNSPSC
12352005
Target
GABA Receptor; Reference Standards
Type
Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bicuculline-standard.html
Smiles
O=C1O[C@@H]([C@H]2N(C)CCC3=C2C=C(OCO4)C4=C3)C5=CC=C(OCO6)C6=C51
Molecular Formula
C20H17NO6
Molecular Weight
367.35
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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