L-Thyroxine (sodium salt pentahydrate)
Product Specifications
UNSPSC Description
L-Thyroxine sodium salt pentahydrate (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1].
Target Antigen
Endogenous Metabolite; Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/L-Thyroxine-sodium-salt-pentahydrate.html
Purity
99.91
Solubility
DMSO : ≥ 28 mg/mL|H2O : < 0.1 mg/mL
Smiles
N[C@@H](CC1=CC(I)=C(C(I)=C1)OC2=CC(I)=C(O)C(I)=C2)C(O[Na])=O.O.O.O.O.O
Molecular Weight
888.93
References & Citations
[1]Arici M, et al. Association between genetic polymorphism and levothyroxine bioavailability in hypothyroid patients. Endocr J. 2018 Mar 28;65(3):317-323.|[2]Corriveau S, et al. Levothyroxine treatment generates an abnormal uterine contractility patterns in an in vitro animalmodel. J Clin Transl Endocrinol. 2015 Sep 9;2(4):144-149.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18341A/L-Thyroxine-sodium-salt-pentahydrate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18341A/L-Thyroxine-sodium-salt-pentahydrate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
6106-07-6
Available Sizes
Curated Selection
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