Flotillin-2 Recombinant Rabbit Monoclonal Antibody [PSH03-41]

Flotillin-2 is a protein that in humans is encoded by the FLOT2 gene. Flotillin 2 (flot-2) is a highly conserved protein isolated from caveolae/lipid raft domains that tether growth factor receptors linked to signal transduction pathways. Flot-2 binds to PAR-1, a known upstream mediator of major signal transduction pathways implicated in cell growth and metastasis, and may influence tumour progression. Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. This gene encodes a caveolae-associated, integral membrane protein, which is thought to function in neuronal signaling.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

ECS-1 antibody ECS1 antibody Epidermal surface antigen 1 antibody Epidermal surface antigen antibody ESA antibody ESA1 antibody Flot2 antibody FLOT2_HUMAN antibody Flotillin 2 (epidermal surface antigen 1) antibody Flotillin-2 antibody M17S1 antibody Membrane component chromosome 17 surface marker 1 antibody Membrane component chromosome 17 surface marker 1 homolog antibody membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1) antibody Membrane component, chromosome 17, surface marker 1 antibody REG-1 antibody Reggie-1 antibody Reggie-2 antibody

Abbreviation

FLOT2, ESA1, M17S1

Swiss Prot

Q14254 Human, Q60634 Mouse, Q9Z2S9 Rat

Cellular Locus

Cell membrane, Membrane, caveola, Endosome, Membrane.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat,Monkey

Immunogen

Recombinant protein within human Flotillin-2 aa 1-428 / 428.

Isotype

IgG

Clone

PSH03-41

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell, FC

Positive Control

HeLa cell lysate, A431 cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse lung tissue lysate, rat lung tissue lysate, HeLa, 293T cell lysate, A549 cell lysate, MCF7 cell lysate, human lung tissue lysate, mouse skin tissue lysate, rat skin tissue lysate, NIH/3T3, PC-12, human breast cancer tissue, human liver cancer tissue, mouse lung tissue, rat lung tissue.