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Mivebresib-alkyne

Mivebresib-alkyne (Compound 25), a Mivebresib derivative, can be used for BRD4 targeted PROTAC synthesis through click reaction[1].

Product Specifications

CAS Number

2409674-37-7

UNSPSC

12352005

Target

Epigenetic Reader Domain; Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

Epigenetics; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mivebresib-alkyne.html

Smiles

O=C(C(N1)=CC(C(C2=CC(NS(=O)(CC)=O)=CC=C2OC3=CC=C(F)C=C3F)=CN4C)=C1C4=O)NCC#C

Molecular Formula

C26H22F2N4O5S

Molecular Weight

540.54

References & Citations

[1]Zhang J, et al. Development of small-molecule BRD4 degraders based on pyrrolopyridone derivative. Bioorg Chem. 2020 Jun;99:103817.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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