CEAM6 rabbit pAb
This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014],
Product Specifications
Background
UniProt
P40199
Swiss Prot
P40199
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human CEAM6
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; WB
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, WB 1:500-2000
Molecular Weight
37kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
37kD
Fragment
IgG
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor . Apical cell membrane . Cell surface . Localized to the apical glycocalyx surface. .
Other Product Names
Carcinoembryonic antigen-related cell adhesion molecule 6 (Non-specific crossreacting antigen; Normal cross-reacting antigen; CD antigen CD66c)
Gene ID (Human)
4680
Available Sizes
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