HIV-1 inhibitor-65
HIV-1 inhibitor-65 (compound 3c) is an inhibitor of HIV-1 (EC50: 2.9 nM) and an activator of protein kinase C (PKC) . HIV-1 inhibitor-65 inhibits syncytium formation (EC50: 7.0 nM) and inhibits HIV-1 entry and HIV-1 reverse transcriptase[1].
Product Specifications
UNSPSC
12352005
Target
HIV; PKC; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection; Epigenetics; TGF-beta/Smad
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-65.html
Solubility
10 mM in DMSO
Smiles
CCC1=C[C@@]2([H])[C@@](C3(C)C)([H])[C@@]3(OC(CCCCCCCCC)=O)[C@H](C(/C=C/C4=CC=C(F)C=C4)=O)[C@@H](C)[C@@]2([C@@]([H])([C@@]5(C1)O)C=C(C5=O)C)O
Molecular Formula
C40H53FO6
Molecular Weight
648.84
References & Citations
[1]Huang X, et al. Synthesis and anti-HIV activities of phorbol derivatives. Chin J Nat Med. 2024 Feb;22 (2) :146-160.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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