Cytidine-5'-triphosphate

Cytidine 5′-triphosphate (Cytidine triphosphate; 5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP) . Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii[1].

Product Specifications

CAS Number

[65-47-4]

Product Name Alternative

Cytidine triphosphate; 5'-CTP

UNSPSC

12352005

Hazard Statement

H315, H319

Target

DNA/RNA Synthesis; Endogenous Metabolite; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/cytidine-5-triphosphate.html

Purity

98.0

Solubility

H2O : ≥ 200 mg/mL

Smiles

O[C@H]1[C@@H](O)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1COP(OP(OP(O)(O)=O)(O)=O)(O)=O

Molecular Formula

C9H16N3O14P3

Molecular Weight

483.16

Precautions

H315, H319

References & Citations

[1]Heidy Y Narvaez-Ortiz, et al. A CTP Synthase Undergoing Stage-Specific Spatial Expression Is Essential for the Survival of the Intracellular Parasite Toxoplasma gondii. Front Cell Infect Microbiol. 2018 Mar 22;8:83.|[2]Hatch GM, et al., Regulation of cardiolipin biosynthesis in H9c2 cardiac myoblasts by cytidine 5'-triphosphate. J Biol Chem. 1996 Oct 18;271 (42) :25810-6.|[3]Matsumoto S, et al., An equilibrium binding study of the interaction of aspartate transcarbamylase with cytidine 5'-triphosphate and adenosine 5'-triphosphate. Biochemistry. 1973 Mar 27;12 (7) :1388-94.