(E) -2-Hydroxycinnamaldehyde

(E) -2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E) -2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E) -2-Hydroxycinnamaldehyde has antitumor activity[1].

Product Specifications

CAS Number

[60125-23-7]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Apoptosis; Reactive Oxygen Species (ROS) ; STAT

Type

Natural Products

Related Pathways

Apoptosis; Immunology/Inflammation; JAK/STAT Signaling; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e-2-hydroxycinnamaldehyde.html

Purity

99.83

Solubility

DMSO : 350 mg/mL (ultrasonic)

Smiles

O=C/C=C/C1=C(C=CC=C1)O

Molecular Formula

C9H8O2

Molecular Weight

148.16

Precautions

H315, H319

References & Citations

[1]Yoon YJ, et al. 2'-Hydroxycinnamaldehyde inhibits proliferation and induces apoptosis via signal transducer and activator of transcription 3 inactivation and reactive oxygen species generation. Cancer Sci. 2019 Jan;110 (1) :366-378.