CD79b Antibody (MMAE)
Anti-CD79b Reference Antibodyected antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
Product Specifications
UniProt
P40259
Reactivity
Human
Target
CD79b
Clonality
Recombinant
Conjugation
MMAE
Field of Research
Immunology & Inflammation
Purification
Protein A
Concentration
Batch dependent
Purity
>95%
Molecular Weight
150.53 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, FA, FACS, In vivo
Preservative
100 mM Proline/Acetic acid 20mM Arginine pH 5.0
Available Sizes
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