Human Calpain 1 Protein

<strong>Human Calpain 1 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2014153_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ‚â•1000 U/mg_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20¬∞C_x000D_ <strong>Keywords:</strong> Calcium-activated neutral protease 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Baudry M, Bi X. Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration Trends Neurosci. 2016 Apr;39(4):235-245._x000D_ 2: Wang L, Zhang C, Sun S, Chen Y, Hu Y, Wang H, Liu M, Dong N, Wu Q. Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells Biochem J. 2019 Aug 28;476(16):2355-2369._x000D_ 3: Sparatore B, Pedrazzi M, Garuti A, Franchi A, Averna M, Ballestrero A, De Tullio R. A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation Biochim Biophys Acta Mol Cell Res. 2019 Aug;1866(8):1260-1271._x000D_ 4: Hsu CY, Gasc G, Raymond AA, Burlet-Schiltz O, Takahara H, Serre G, Mchin MC, Simon M. Deimination of Human Hornerin Enhances its Processing by Calpain-1 and its Cross-Linking by Transglutaminases J Invest Dermatol. 2017 Feb;137(2):422-429._x000D_ 5: Shinkai-Ouchi F, Shindo M, Doi N, Hata S, Ono Y. Calpain-2 participates in the process of calpain-1 inactivation Biosci Rep. 2020 Nov 27;40(11):BSR20200552._x000D_ 6: Miller DJ, Adams SE, Hallett MB, Allemann RK. Calpain-1 inhibitors for selective treatment of rheumatoid arthritis: what is the future? Future Med Chem. 2013 Nov;5(17):2057-74._x000D_ 7: Li RY, Zheng ZY, Li ZM, Heng JH, Zheng YQ, Deng DX, Xu XE, Liao LD, Lin W, Xu HY, Huang HC, Li EM, Xu LY. Cisplatin-induced pyroptosis is mediated via the CAPN1/CAPN2-BAK/BAX-caspase-9-caspase-3-GSDME axis in esophageal cancer Chem Biol Interact. 2022 Jul 1;361:109967._x000D_ 8: Upla P, Marjom_ki V, Nissinen L, Nylund C, Waris M, Hyypi_ T, Heino J. Calpain 1 and 2 are required for RNA replication of echovirus 1 J Virol. 2008 Feb;82(3):1581-90._x000D_ 9: Ruppert AM, Baud L, Rabbe N, Perez J, Duruisseaux M, Vieira T, Antoine M, Cadranel J, Wislez M. Calpain 1 in bronchoalveolar lavage fluid is associated with poor prognosis in lepidic predominant pulmonary adenocarcinoma Bull Cancer. 2019 Mar;106(3):179-188._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34524407">10: Wang J, Ciampa G, Zheng D, Shi Q, Chen B, Abel ED, Peng T, Hall DD, Song LS. Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy Biochem J. 2021 Oct 15;478(19):3539-3553. </a>_x000D_ _x000D_ <strong>Products Related to Human Calpain 1 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>