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(Phenylac1, D-Tyr (Et) 2, Lys6, Arg8, des-Gly9) -Vasopressin

Selected Variant

HY-P4683

Size: 1 Each

(Phenylac1, D-Tyr (Et) 2, Lys6, Arg8, des-Gly9) -Vasopressin is a potent vasopressin V1 receptor (VP V1R) antagonist. (Phenylac1, D-Tyr (Et) 2, Lys6, Arg8, des-Gly9) -Vasopressin significantly decreases the mean arterial pressure (MAP) in rats[1].

Product Specifications

CAS Number

129520-65-6

UNSPSC

12352209

Target

Vasopressin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/phenylac1-d-tyr-et-2-lys6-arg8-des-gly9-vasopressin.html

Solubility

10 mM in DMSO

Smiles

CCOC(C=C1)=CC=C1C[C@@H](NC(CC2=CC=CC=C2)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O

Molecular Formula

C54H76N14O11

Molecular Weight

1097.27

References & Citations

[1]Levi DI, et al. High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons. Cell Rep. 2021 Mar 16;34 (11) :108866.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

V1a Receptor

Price

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