(S) -GNE-140
(S) -GNE-140 is the less active enantiomer of GNE-140 which can inhibit Lactate dehydrogenase A (LDHA) .
Product Specifications
CAS Number
[2003234-64-6]
UNSPSC
12352005
Target
Lactate Dehydrogenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/_S_-GNE-140.html
Purity
99.30
Solubility
DMSO : ≥ 14.29 mg/mL
Smiles
O=C1N[C@](C2=CSC=C2)(C3=CC=C(N4CCOCC4)C=C3)CC(O)=C1SC5=CC=CC=C5Cl
Molecular Formula
C25H23ClN2O3S2
Molecular Weight
499.04
References & Citations
[1]Purkey HE, et al. Cell Active Hydroxylactam Inhibitors of Human Lactate Dehydrogenase with Oral Bioavailability in Mice. ACS Med Chem Lett. 2016 Aug 26;7 (10) :896-901.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
LDHA
Available Sizes
Curated Selection
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