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PM-1

Product Specifications

UNSPSC Description

PM-1, a derivative of Thioflavin-T (ThT; HY-D0218), is a small but highly specific plasma membrane (PM) fluorescent dye for specific and long-time membrane imaging of living and fixed cells. PM-1 is embedded directly into the cell membrane and exhibits a very long retention time on the plasma membrane with a half-life of approximately 15 h. PM-1 can be used in combination with protein labeling probes to study ectodomain shedding and endocytosis processes of cell surface proteins[1].

Target Antigen

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pm-1.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(CCNC1=CC=C(C=C1)C2=NC3=CC=CC=C3S2)=O

Molecular Weight

298.36

References & Citations

[1]Shun-Qiang Xu, et al. Small Plasma Membrane-Targeted Fluorescent Dye for Long-Time Imaging and Protein Degradation Analyses. nal Chem. 2023 Oct 24;95(42):15549-15555.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-156404/PM-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-156404/PM-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1449483-78-6

Available Sizes

Curated Selection

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