5 (R) -HETE

5 (R) -HETE is a lipoxygenase product of arachidonic acid. 5 (R) -HETE is an inducer of neutrophil migration through endothelial and epithelial barriers. 5 (R) -HETE is important in mediating lung inflammatory processes[1].

Product Specifications

CAS Number

[61641-47-2]

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-r-hete.html

Solubility

10 mM in DMSO

Smiles

CCCCC/C=C\C/C=C\C/C=C\C=C\[C@H](O)CCCC(O)=O

Molecular Formula

C20H32O3

Molecular Weight

320.47

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]D B Bittleman, et al. 5-Hydroxyeicosatetraenoic acid (HETE) -induced neutrophil transcellular migration is dependent upon enantiomeric structure. Am J Respir Cell Mol Biol. 1995 Mar;12 (3) :260-7.