Candoxatrilat
Candoxatrilat (UK 73967) is an orally active inhibitor of neutral endopeptidase. By elevating the levels of atrial natriuretic peptides, Candoxatrilat exerts its diuretic and natriuretic effects. Candoxatrilat is utilized in the research of heart failure[1].
Product Specifications
CAS Number
123122-54-3
Product Name Alternative
UK 73967
UNSPSC
12352211
Target
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/candoxatrilat.html
Smiles
COCCOC[C@H](CC1(C(N[C@H]2CC[C@@H](C(O)=O)CC2)=O)CCCC1)C(O)=O
Molecular Formula
C20H33NO7
Molecular Weight
399.48
References & Citations
[1]Ksye B, et al. Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril[J]. Xenobiotica, 1997, 27 (10) : 1091-1102.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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