Brecanavir
Brecanavir (GW640385) is a novel, potent HIV protease inhibitor.
Product Specifications
CAS Number
313682-08-5
Product Name Alternative
GW640385
UNSPSC
12352005
Target
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/brecanavir.html
Purity
98.79
Solubility
DMSO : 17.6 mg/mL (ultrasonic; warming)
Smiles
CC1=NC(COC2=CC=C(C[C@H](NC(O[C@H]3CO[C@@H]4[C@H]3CCO4)=O)[C@H](O)CN(S(=O)(C5=CC=C6C(OCO6)=C5)=O)CC(C)C)C=C2)=CS1
Molecular Formula
C33H41N3O10S2
Molecular Weight
703.82
References & Citations
[1]Ford SL, Reddy YS, Anderson MT, et al. Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor. Antimicrob Agents Chemother. 2006;50 (6) :2201-2206. |[2]Reddy YS, Ford SL, Anderson MT, Murray SC, Ng-Cashin J, Johnson MA. Safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus type 1 protease inhibitor, following repeat administration with and without ritonavir in healthy adult subjects. Antimicrob Agents Chemother. 2007;51 (4) :1202-1208.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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