Human CDC25A Protein

<strong>Human CDC25A Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011897_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 0.25 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> EC 3.1.3.48 protein, Cell division cycle 25A isoform b protein, M-phase inducer phosphatase 1 protein, CDC25A, CDC 25A CDC-25A protein, CDC 25A protein, Dual specificity phosphatase Cdc25A protein, D9Ertd393e protein, Cell division cycle 25A isoform a pro_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang C, Zeng J, Li LJ, Xue M, He SL. Cdc25A inhibits autophagy-mediated ferroptosis by upregulating ErbB2 through PKM2 dephosphorylation in cervical cancer cells Cell Death Dis. 2021 Nov 6;12(11):1055._x000D_ 2: Brunetto E, Ferrara AM, Rampoldi F, Talarico A, Cin ED, Grassini G, Spagnuolo L, Sassi I, Ferro A, Cuorvo LV, Barbareschi M, Piccinin S, Maestro R, Pecciarini L, Doglioni C, Cangi MG. CDC25A protein stability represents a previously unrecognized target of HER2 signaling in human breast cancer: implication for a potential clinical relevance in trastuzumab treatment Neoplasia. 2013 Jun;15(6):579-90._x000D_ 3: Chandrasekaran AP, Woo SH, Sarodaya N, Rhie BH, Tyagi A, Das S, Suresh B, Ko NR, Oh SJ, Kim KS, Ramakrishna S. Ubiquitin-Specific Protease 29 Regulates Cdc25A-Mediated Tumorigenesis Int J Mol Sci. 2021 May 28;22(11):5766._x000D_ 4: Zhao S, Wang Y, Guo T, Yu W, Li J, Tang Z, Yu Z, Zhao L, Zhang Y, Wang Z, Wang P, Li Y, Li F, Sun Z, Xuan Y, Tang R, Deng WG, Guo W, Gu C. YBX1 regulates tumor growth via CDC25a pathway in human lung adenocarcinoma Oncotarget. 2016 Dec 13;7(50):82139-82157._x000D_ 5: Esteban V, Vázquez-Novelle MD, Calvo E, Bueno A, Sacristán MP. Human Cdc14A reverses CDK1 phosphorylation of Cdc25A on serines 115 and 320 Cell Cycle. 2006 Dec;5(24):2894-8._x000D_ 6: Lin YM, Chung CL, Cheng YS. Posttranscriptional regulation of CDC25A by BOLL is a conserved fertility mechanism essential for human spermatogenesis J Clin Endocrinol Metab. 2009 Jul;94(7):2650-7._x000D_ 7: Parsons R. Phosphatases and tumorigenesis Curr Opin Oncol. 1998 Jan;10(1):88-91._x000D_ 8: Wang Z, Zhang B, Wang M, Carr BI. Cdc25A and ERK interaction: EGFR-independent ERK activation by a protein phosphatase Cdc25A inhibitor, compound 5 J Cell Physiol. 2005 Aug;204(2):437-44._x000D_ 9: Shen T, Huang S. The role of Cdc25A in the regulation of cell proliferation and apoptosis Anticancer Agents Med Chem. 2012 Jul;12(6):631-9._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34761581">10: Jiang T, Cheng H. miR-34a-5p blocks cervical cancer growth and migration by downregulating CDC25A J BUON. 2021 Sep-Oct;26(5):1768-1774.</a>_x000D_ _x000D_ <strong>Products Related to Human CDC25A Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>