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GPX4-IN-2

GPX4-IN-2 is a potent GPX4 inhibitor. GPX4 shows antiproliferative activity. GPX4-IN-2 has the potential for the research of cancer[1].

Product Specifications

CAS Number

[2485005-22-7]

UNSPSC

12352005

Target

Glutathione Peroxidase

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gpx4-in-2.html

Purity

98.66

Solubility

DMSO : 37.5 mg/mL (ultrasonic)

Smiles

CCCC[C@@H]1N[C@H](C(C(C1)=C2)=CC=C2OC)C3=CC=C(C=C3)NC4(C[C@H](C5)C6)C[C@H]6C[C@H]5C4

Molecular Formula

C30H40N2O

Molecular Weight

444.65

References & Citations

[1]Chun Jiang, et al. Compounds with ferroptosis inducing activity and methods of their use. WO2020176757A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GPX4

Available Sizes

Curated Selection

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