INOs-IN-1
INOs-IN-1 (YPW) is a potent inducible nitric oxide synthase (iNOS) inhibitor. iNOs-IN-1 can significantly inhibit the expression of IL-6 and iNOS, as well as reduce LPS-induced NO generation with dose-dependent manner in mouse macrophages. Anti-inflammatory effects[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related; NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/inos-in-1.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
N[C@@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CNC3=C2C=CC=C3)=O)=O)CC4=CC=C(C=C4)O
Molecular Formula
C25H28N4O5
Molecular Weight
464.51
References & Citations
[1]Peng Y, et al. Identification and molecular mechanism of a tri-peptide inhibitor targeting iNOS from duck embryo protein hydrolysates by experimental and bioinformatics studies. Bioorg Chem. 2022;122:105736.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6; iNOS
Available Sizes
Frequently Asked Questions
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