6-Thioinosine Phosphate
6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine. Azathioprine is a purine analog immunosuppressive drug[1].
Product Specifications
CAS Number
53-83-8
Product Name Alternative
Thioinosinic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/6-thioinosine-phosphate.html
Purity
90.00
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C=NC3=C2N=CNC3=S
Molecular Formula
C10H13N4O7PS
Molecular Weight
364.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Fletcher L, et al. Assay of thioinosinic acid, an active metabolite of azathioprine, in human lymphocytes. Br J Clin Pharmacol. 1980 Sep;10 (3) :287-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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