6-Thioinosine Phosphate

6-Thioinosine Phosphate (Thioinosinic acid) is an intermediate metabolite of azathioprine (HY-B0256) . Azathioprine is a purine analog immunosuppressive drug[1].

Product Specifications

CAS Number

[53-83-8]

Product Name Alternative

Thioinosinic acid

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/6-thioinosine-phosphate.html

Purity

90.00

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(O)(O)=O)O[C@H]1N2C=NC3=C2N=CNC3=S

Molecular Formula

C10H13N4O7PS

Molecular Weight

364.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Fletcher L, et al. Assay of thioinosinic acid, an active metabolite of azathioprine, in human lymphocytes. Br J Clin Pharmacol. 1980 Sep;10 (3) :287-92.