Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor 18 (Compound 9) is a human carbonic anhydrase (hCA) isoform inhibitor, with Kis of 604.8, 333.6, 1.9 and 6.7 nM for hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 18 can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-18.html
Solubility
10 mM in DMSO
Smiles
O=C1C(NC2=CC=C(C=C2)S(=O)(N)=O)=CC(N1C3=CC=C(C=C3)S(=O)(N)=O)C4=CC=C(C=C4)OCCCC
Molecular Formula
C26H28N4O6S2
Molecular Weight
556.65
References & Citations
[1]Al-Matarneh CM, et al. Synthetic Approaches to Novel Human Carbonic Anhydrase Isoform Inhibitors Based on Pyrrol-2-one Moiety. J Med Chem. 2024 Feb 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040008-500 1x 500 µL
MAGE A1 (MA454), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040040-500 1x 500 µL
CD35 / CR1 (E11), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC742848-100 1x 100 µL
Fibronectin (Fn-3), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
