Calpain-2-IN-1
Calpain-2-IN-1 (Formula 1A) is a isoform-specific calpain-2 inhibitor with Kis of 181 nM and 7.8 nM for calpain-1, and calpain-2, respectively. Calpain-2-IN-1 can be used for the research of neurodegenerative diseases and other diseases of synaptic function[1].
Product Specifications
CAS Number
144231-85-6
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/calpain-2-in-1.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(N[C@@H](CC)C(C(NCC2=CC(OC)=CC(OC)=C2)=O)=O)=O
Molecular Formula
C28H37N3O7
Molecular Weight
527.61
References & Citations
[1]Michel Baudry, et al. Isoform-specific calpain inhibitors, methods of identification, and uses thereof. WO2016077461A2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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