MGluR2 modulator 1
MGluR2 modulator 1 (compound 95) is a potent and BBB-penetrated mGluR2 (metabotropic glutamate receptor-2) positive allosteric modulator, with an EC50 of 0.03 μM. mGluR2 modulator 1 can be used for psychosis research[1].
Product Specifications
CAS Number
2671063-84-4
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mglur2-modulator-1.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N(CCN2C1=NC3=C2C=CC=C3)CCCCOC4=CC=C(C=C4)OC(F)(F)F
Molecular Formula
C21H20F3N3O3
Molecular Weight
419.40
References & Citations
[1]Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs) . Eur J Med Chem. 2020 Jan 15;186:111881.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC402315-100 1x 100 µL
Collagen VII (LH7.2), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC471816-500 1x 500 µL
Histone H1 (Pan Nuclear Marker) (N/A), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
E-EL-M0993-01 24 Tests
Mouse SP-D (Pulmonary surfactant-associated protein D) ELISA Kit
Sign In for Pricing
View Details E-EL-M0993-02 48 Tests
Mouse SP-D (Pulmonary surfactant-associated protein D) ELISA Kit
Sign In for Pricing
View Details E-EL-M0993-03 96 Tests
Mouse SP-D (Pulmonary surfactant-associated protein D) ELISA Kit
Sign In for Pricing
View Details