ALK5-IN-80
ALK5-IN-80 (Compound 29b) is a selective ALK5 inhibitor with an IC50 value of 3.7 nM. ALK5-IN-80 can be used for cancer research[1].
Product Specifications
CAS Number
[3039952-63-8]
UNSPSC
12352005
Target
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-80.html
Smiles
O=C(N)C1=C(C2=CC(C(C)=O)=CN2)SC(N(C3CC3)C4=CN(N=C4)C5=C(F)C=NC=C5)=N1
Molecular Formula
C21H18FN7O2S
Molecular Weight
451.48
References & Citations
[1]Arai M, et al. Design and synthesis of novel thiazole-derivatives as potent ALK5 inhibitors. Bioorg Med Chem Lett. 2024 May 16;108:129797.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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